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MAJOR STROKE SYNDROMES AND STROKE MIMICS

The three main divisions of the brain are the cerebrum (including the left and right cerebral hemispheres), the brainstem, and the cerebellum. The signs of a patient with brain injury depend on where in the brain the lesion occurs. Differentiating a stroke from a stroke mimic is based on (1) history of symptom onset (e.g., stroke presents suddenly and with no associated trauma, brain tumors present over weeks to months, seizures present with shaking of a limb or a staring episode, hypoglycemia, often presents after excessive insulin use, subdural hematomas present after head trauma), (2) past medical history (e.g., stroke patients often have vascular risk factors such as hypertension or diabetes, brain tumor patients may have a history of systemic cancer, seizure and migraine patients usually have a history of similar episodes in the past), and (3) laboratory data (e.g., hypoglycemic patients have low blood glucose and computed tomography [CT] scan differentiates stroke from tumor, abscess, and intracranial hemorrhage). Thus, one cannot determine by neurologic examination alone whether an acute stroke is ischemic or hemorrhagic. Based on brain localization, the major stroke syndromes are:

  1. Left Hemisphere
  2. Right Hemisphere
  3. Brainstem
  4. Cerebellum
  5. Possible Hemorrhage


5 Major Syndromes: Typical Signs


FOCAL DEFICITS

LEFT
HEMISPHERE

RIGHT
HEMISPHERE

BRAINSTEM

CEREBELLUM
*

HEMORRAHGIC
+
SPEECH
Aphasia—
Wrong or
Inappropriate
words
Says correctly
Dysarthria—
slurring
Says correctly
Says correctly
but slowly
(often sleepy)
FOCAL
DROOP
Right facial
droop
Left facial
droop
May have
bilateral droop
No droop
No droop
ARM
DRIFT
Right arm drift
(weakness)
Left arm drift
(weakness)
May have
Bilateral drift
(weakness)
No drift
No drift
* Finger-to-nose and/or heel-to-shin testing typically abnormal
+ Decreased level of consciousness with headache and stiff neck are typical; this syndrome without associated focal neurologic deficits is most consistent with subarachnoid hemorrhage. With intracerebral hemorrhage, focal deficits may occur.

 

 

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